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The decline in LVDP was attenuated with 4-ClDzp, with 4-ClDzp treated hearts having significantly higher LVDP from 22 minutes after diamide through the duration of the protocol (Figure 4)

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The mTOR pathway regulates protein synthesis, cytoskeletal remodeling, and synapse formation, contributing to neuronal repair and rapid antidepressant effects observed with PSYs [51,96,97]